{"id":48,"date":"2023-03-21T13:09:32","date_gmt":"2023-03-21T13:09:32","guid":{"rendered":"https:\/\/www.merckconnect.com\/sivextro\/?page_id=48"},"modified":"2025-09-08T10:10:52","modified_gmt":"2025-09-08T10:10:52","slug":"management-of-absssi","status":"publish","type":"page","link":"https:\/\/www.merckconnect.com\/sivextro\/management-of-absssi\/","title":{"rendered":"Management of ABSSSI"},"content":{"rendered":"<link rel='stylesheet' id='vivid360-heading-css-css' href='https:\/\/www.merckconnect.com\/sivextro\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/heading\/css\/style.min.css?ver=1766071753' media='all' \/>\n\n<div class=\"vivid360-heading default-hcp-fontsize default-hcp-tablet-fontsize default-hcp-mobile-fontsize\" id=\"a4907fb91-3b77-4d98-a966-c1507cb2df6e\"><h1 class=\"content-width fontWeightRegular\" style=\"--desktopFontSize:var(--h1FontSizeDesktop);--tabletFontSize:var(--h1FontSizeDesktop);--mobileFontSize:var(--h1FontSizeMobile);--desktopLineHeightSize:var(--h1LineHeightDesktop);--tabletLineHeightSize:var(--h1LineHeightDesktop);--mobileLineHeightSize:\" id=\"\"><strong>Management of Acute Bacterial Skin and Skin Structure Infections (ABSSSI)<\/strong><\/h1><\/div>\n\n\n<link rel='stylesheet' id='vivid360-spacer-css-css' href='https:\/\/www.merckconnect.com\/sivextro\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/spacer\/css\/style.min.css?ver=1766071753' media='all' \/>\n\n<div style=\"background-color:transparent;height:8px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-8\"><\/div>\n\n\n\n<p>Many patients with ABSSSI may not require inpatient treatment and could be treated on an outpatient basis with oral antibacterial drugs.<sup>1<\/sup><\/p>\n\n\n\n<div style=\"background-color:transparent;height:8px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-8 spacer-undefined\"><\/div>\n\n\n\n<p>Outpatient settings may include primary care office, urgent care centers, or wound care centers.<\/p>\n\n\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n\n<div class=\"vivid360-heading default-hcp-fontsize default-hcp-tablet-fontsize default-hcp-mobile-fontsize\" id=\"aa3b198d3-c7ef-4684-a6e1-690923740152\"><h2 class=\"content-width fontWeightRegular\" style=\"--desktopFontSize:var(--h2FontSizeDesktop);--tabletFontSize:var(--h2FontSizeDesktop);--mobileFontSize:var(--h2FontSizeMobile);--desktopLineHeightSize:var(--h2LineHeightDesktop);--tabletLineHeightSize:var(--h2LineHeightDesktop);--mobileLineHeightSize:\" id=\"\"><strong>Considerations for treatment<\/strong><\/h2><\/div>\n\n\n\n<p>Infection severity, severe comorbidities, and age (\u226575 years of age) can influence the treatment location decision. Mild ABSSSI and adherence most strongly influenced all treatment decisions to outpatient care.<sup>2<\/sup><\/p>\n\n\n\n<div style=\"background-color:transparent;height:8px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-8 spacer-undefined\"><\/div>\n\n\n\n<div class=\"vivid360-heading\" id=\"a762e81d8-a879-41e3-ab1c-b9d315041efb\"><h3 class=\"content-width fontWeightRegular\" style=\"--desktopFontSize:var(--h3FontSizeDesktop);--tabletFontSize:var(--h3FontSizeDesktop);--mobileFontSize:var(--h3FontSizeMobile);--desktopLineHeightSize:var(--h3LineHeightDesktop);--tabletLineHeightSize:var(--h3LineHeightDesktop);--mobileLineHeightSize:\" id=\"\"><strong>Outpatient management strategies<\/strong><\/h3><\/div>\n\n\n\n<p>Management strategies for outpatient ABSSSI treatment include close follow-up care and oral antibacterial drugs.<sup>1<\/sup><\/p>\n\n\n\n<div style=\"background-color:transparent;height:16px\" class=\"wp-block-vivid360-spacer vivid360-spacer spacer-16\"><\/div>\n\n\n\n<div class=\"vivid360-heading\" id=\"aecd31158-bfbe-48e6-9f0b-2e6ff39a9c73\"><h4 class=\"content-width fontWeightRegular\" style=\"--desktopFontSize:var(--h4FontSizeDesktop);--tabletFontSize:var(--h4FontSizeDesktop);--mobileFontSize:var(--h4FontSizeMobile);--desktopLineHeightSize:var(--h4LineHeightDesktop);--tabletLineHeightSize:var(--h4LineHeightDesktop);--mobileLineHeightSize:\" id=\"\"><strong>References:<\/strong><\/h4><\/div>\n\n\n<link rel='stylesheet' id='vivid360-list-css-css' href='https:\/\/www.merckconnect.com\/sivextro\/wp-content\/themes\/cex-wpvip-mhh-merck-vivid360-theme-1-12\/blocks\/list\/css\/style.min.css?ver=1766071753' media='all' \/>\n\n<div class=\"vivid-block-list content-width  block-385c3027-72bd-4e4b-a5ed-09dde408649d bullets-bold\" data-image=\"\" data-image-mobile=\"\" data-image-all=\"\" data-image-all-mobile=\"\" data-icon-color=\"#333\" data-text-color=\"#333\" data-client-id=\"block-385c3027-72bd-4e4b-a5ed-09dde408649d\"><ol class=\"first-level default-order\"><li>Pollack CV Jr, Amin A, Ford WT Jr, et al. Acute Bacterial Skin and Skin Structure Infections (ABSSSI): practice guidelines for management and care transitions in the emergency department and hospital.<em> J Emerg Med.<\/em> 2015;48(4):508-519.<\/li><li>Lane S, Johnston K, Sulham KA, et al. Identification of patient characteristics influencing setting of care decisions for patients with acute bacterial skin and skin structure infections: Results of a discrete choice experiment.<em> Clin Ther.<\/em> 2016;38(3):531-544.<\/li><\/ol><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Many patients with ABSSSI may not require inpatient treatment and could be treated on an outpatient basis with oral antibacterial drugs.1 Outpatient&#8230;<\/p>\n","protected":false},"author":665,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_trash_the_other_posts":false,"editor_notices":[],"footnotes":""},"ga4_page_audience":[],"ga4_page_birn_id":[],"ga4_page_branding":[267],"ga4_page_businessunit":[272],"ga4_page_campaign":[],"ga4_page_content_purpose":[287],"ga4_page_customer_journey_stage":[333],"ga4_page_customer_specialty":[351],"ga4_page_experience":[],"ga4_page_indication":[403],"ga4_page_material_intent":[530],"ga4_page_product":[697],"ga4_page_region":[845],"ga4_page_therapeuticarea":[869],"user_role":[],"mhh-area-of-interest":[],"access":[],"user_status":[],"class_list":["post-48","page","type-page","status-publish"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Acute Bacterial Skin and Skin Structure Infections (ABSSSI) 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